What casino game has the best odds? Video poker can provide the best odds in a casino, depending on the version of the paytable. However, blackjack is generally regarded as having the best casino odds when using basic strategy. This can help lower the house edge to around 0.50%.

The online casino with the best payouts in the US is BetMGM. This site has an extensive library of 800+ casino games and an overall average RTP of 98.3%. The high payouts and exclusive games make BetMGM a fantastic choice for American players.

With an average payout percentage of 95.73%, BetMGM is one of the highest-paying online casinos. Its game selection includes high RTP games like NetEnt's Blood Suckers (98%), Starmania from NetGen (97.87%), and Light and Wonder's Quick Hit Pays Eagle's Peak (96.89%), perfect for players who want high RTP games.

While all casino games have their appeal, Blackjack has the highest winning odds, offering a 92% probability of getting the best hand possible, with a 0.5% likely House Edge.